General Cell Based Assays
Eurofins Discoverx PathHunter eXpress TRHR CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0239E2CP0L)
The PathHunter TRHR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. TRH) based activation of TRHR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged TRHR and EA-tagged β-Arrestin-2. Activation of TRHR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress PTAFR CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0236E2CP0L)
The PathHunter PTAFR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. PAF) based activation of PTAFR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged PTAFR and EA-tagged β-Arrestin-2. Activation of PTAFR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress AGTRL1 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0250E2CP0M)
The PathHunter AGTRL1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. apelin-13) based activation of AGTRL1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged AGTRL1 and EA-tagged β-Arrestin-2. Activation of AGTRL1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress UTR2 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0283E2CP2M)
The PathHunter UTR2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. urotensin) based activation of UTR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged UTR2 and EA-tagged β-Arrestin-2. Activation of UTR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Optimize Technologies EXP Discovery Kit - Contains 1 holder and 3 trap cartridge packs (total of 9 traps). Create your custom kit by choosing a holder (Direct Connect or In-Line) and any 3 of the cartridge configurations.
The patent-pending Hand-Tight EXP™ Trap Column is rated for use at 20,000+ psi (1,400+ bar). This unique design connects directly to any injection valve (with 10-32 threads) or in-line with 1/16” stainless tubing for unparalleled convenience and efficiency. The EXP™ Cartridge System enables chemists to quickly remove detergents or salts which can affect the ionization process in MS work. This trapping technique can concentrate the sample directly on-line, allowing for increased recovery of precious sample material compared to off-line techniques. On-line trapping readily lends itself to automation for high-throughput analysis in UHPLC/MS applications. Free-Turn™ architecture allows the user to change cartridges by hand without breaking fluid connections on the holder inlet/outlet.
Eurofins Discoverx PathHunter eXpress CCKAR Activated GPCR Internalization Assay, 10pl Kit. (93-0650E3CP5L)
The PathHunter CCKAR Activated GPCR internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of CCKAR via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged CCKAR. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting CCKAR-arrestin complex is internalized to the early endosome, leading to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
ABclonal Technology PLTP Rabbit mAb
The protein encoded by this gene is one of at least two lipid transfer proteins found in human plasma. The encoded protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the size of HDL particles, this protein may be involved in cholesterol metabolism. At least two transcript variants encoding different isoforms have been found for this gene.
Eurofins Discoverx PathHunter eXpress GPR35 Activated GPCR Internalization Assay, 10pl Kit. (93-0968E3CP5L)
The PathHunter GPR35 Activated GPCR internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of GPR35 via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged GPR35. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting GPR35-arrestin complex is internalized to the early endosome, leading to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
AnaSpec SensoLyte Red Glucocerebrosidase (GBA) Assay Kit *Fluorimetric*
The SensoLyte Red Glucocerebrosidase (GBA) Assay Kit detects GBA activity by using a highly sensitive fluorogenic substrate. The GBA substrate provided in the kit releases the red fluorescent dye resorufin upon Glucocerebrosidase cleavage with absorption/emission maxima at 570 nm/610 nm. This assay kit can be used to detect enzyme activity in purified enzyme preparations and compound screening. The Red Glucocerebrosidase (GBA) Assay is one-step homogenous reaction, which does not require the additional step of dispensing stop solution after the incubation, thereby suitable for HTS. The long wavelength fluorescence resorufin is also less interfered by the autofluorescence of components in biological samples and test compounds.
Cell Signaling Technology Griess Reagent Nitrite Measurement Kit 1 Kit
Griess Reagent Nitrite Measurement Kit 1 Kit
PHYTO AB INC NADP-ME2 Antibody Immunogen: AT5G11670 Background: NADP-ME2 has been involved in sugar metabolism in veins and in the oxidative burst triggered by hemibiotrophic fungal infection. 150ug/EA
PhytoAB Inc. is a contract research organization and plant antibody R&D based services and products supplier. PhytoAB is privately owned company headquatered in the San Francisco Bay Area of California, USA. PhytoAB specializes in antibody production for plant scientic usage and customized services, focus on the current need of plant antibodies to assist the further investigation of the current booming results from deep genome sequencing and increasing protomics studies. We have specialized R&D and customer services teams to fulfill the needs of botany & plant sciences research and industry world wide with high quality, professional and cutting edge services, and offering complete products usage guidance and suggestions for related problem solutions.
Eurofins Discoverx PathHunter Detection Kit, 550 (100 plates), 40,000 dp (384-well). (93-0001L)
The PathHunter Detection Kit is a detection kit intended for use with Eurofins DiscoverX's PathHunter cell lines or with custom cell lines made using ProLabel/PK expression vectors. This kit contains lysis buffer and EFC substrate to allow for detection of EFC levels in the assayed cells. This kit contains all components required to assay 100 plates (96/384 well). For detailed product information, User manual and COA, visit www.discoverx.com/products/reagents/detection-kit-93-0001l.
Eurofins Discoverx PathHunter eXpress GPR50 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0648E2CP1L)
The PathHunter GPR50 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR50 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR50 and EA-tagged β-Arrestin-2. Activation of GPR50 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.